PUBLICATIONS to 2002:

Epithelia

R.J.Walters.  Ion channel regulation in small intestinal crypts.  Ph.D. Thesis. (1993).  Cambridge University Library.

Walters RJ, Sepulveda FV.

A basolateral K+ conductance modulated by carbachol dominates the membrane potential of small intestinal crypts.
Pflugers Arch. 1991 Nov;419(5):537-9.

 

O'Brien JA, Walters RJ, Sepulveda FV.

Regulatory volume decrease in small intestinal crypts is inhibited by K+ and Cl- channel blockers. Biochim Biophys Acta. 1991 Dec 9;1070(2):501-4.

 

Walters RJ, O'Brien JA, Valverde MA, Sepulveda FV.

Membrane conductance and cell volume changes evoked by vasoactive intestinal polypeptide and carbachol in small intestinal crypts. Pflugers Arch. 1992 Sep;421(6):598-605.

 

O'Brien JA, Walters RJ, Valverde MA, Sepulveda FV.

Regulatory volume increase after hypertonicity- or vasoactive-intestinal-peptide-induced cell-volume decrease in small-intestinal crypts is dependent on Na(+)-K(+)-2Cl- cotransport. Pflugers Arch. 1993 Apr;423(1-2):67-73.

R.J.Walters, F.V.Sepulveda. Ca2+ and voltage-dependence of K+ channels in the crypt basolateral membrane. Biophys.J., Abstract, W115, Baltimore 1996.

F.V.Sepulveda, R.J.Walters. The stage of enterocyte differentiation determines resting potential and agonist responses. Exp. Biol.'96, Washington D.C. abstract 3104, FASEB J.

Growth factors

Stephens L, Cooke FT, Walters R, Jackson T, Volinia S, Gout I, Waterfield MD, Hawkins PT.

Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells. Curr Biol. 1994 Mar 1;4(3):203-14.

P.T.Hawkins, A.Eguinoa, R-G.Qiu, D.Stokoe, F.T.Cooke, R.Walters, S.Wennstrom, L.Claesson-Welsh, T.Evans, M.Symons, L.Stephens. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide-3-kinase. Current Biology, 5, 393-403 (1995).

Walters RJ, Hawkins P, Cooke FT, Eguinoa A, Stephens LR.

Insulin and ATP stimulate actin polymerization in U937 cells by a wortmannin-sensitive mechanism. FEBS Lett. 1996 Aug 19;392(1):66-70.

Neuroscience

R.J.Walters, S.Nawy. Modulation of the retinal On-bipolar cell mGluR6 cascade by phosphorylation. Soc. for Neurosci. abstract, 435.2, San Diego 1995.

R.J.Walters. Seeing a change against the light: how neural circuits are adapted in the retina. New York Science Times Article, June 1996.

M.L.Chandler, I.H.Pang, R.Doshi, E.M.Wexler, R.J.Walters, S.Nawy, L.DeSantis, M.A.Kapin. In vitro and in vivo protective effects of eliprodil in the retina. Investigative Ophthalmology and Visual Science 1997, 38, No.4, Pt1, p.725, Abstract

Walters RJ, Kramer RH, Nawy S.

Regulation of cGMP-dependent current in On bipolar cells by calcium/calmodulin-dependent kinase. Vis Neurosci. 1998 Mar-Apr;15(2):257-61.

Nawy, S., R.J.Walters. Modulation by PKA of the responses to L-AP4 in retinal bipolar cells. Soc. for Neurosci. abstract, 498.12, New Orleans, 1997.

Amin, J., Pollock, V., Walters, R.J. A novel r1 GABA receptor channel with slowed kinetics.  ARVO Abstract, Ft.Lauderdale, FL, May, 2000.

Walters RJ, Hadley SH, Morris KD, Amin J.

Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms. Nat Neurosci. 2000 Dec;3(12):1274-81.

 

Walters, R.J., Amin, J. Slowed kinetics of r1 receptors upon substitution at S439 correlate positively with both side chain volume and hydrophobicity (in preparation).

Brandt, M.V., Walters, R.J., Willenberg, H.S, Scherbaum, W.A., Bornstein, S.R. Nerve Growth Factor Increases Expression of Tyrosine Hydroxylase in Serum-Starved PC12 Pheochromocytoma Cells. Endocrine Soc. Abst., San Francisco, 2002.

Walters, R.J., Rosenbaum, C, Willenberg, H.S., Ehrhart-Bornstein, M, Muller, H-W, Siebler, M., Scherbaum, W.A., Bornstein, S.R. Insulin Induces Increased Expression and Focal Clustering of GABA-A Receptors in PC12 Cells. Endocrine Soc. Abst. (platform), San Francisco, 2002.

Walters, R.J., Rosenbaum, C., Willenberg H.S., Scherbaum, W.A., Bornstein S.R. "Insulin, Nerve Growth Factor and PACAP modulate the expression of GABAA subunits in PC12 Cells" Neuroscience-Net 2002-1.

Ca2+ channels

Walters, RJ. Synergistic activation of G- and L-type Ca2+ channels by D-glucose and membrane depolarization in pancreatic b-cells. Soc.for Neurosci. Abstract (plat), New Orleans, 2000.

AIDS/HIV

R.J.Walters. A fourth strategy to contain the threat of HIV and AIDS? New York Science Times Article February 1996.


Illustration is of crypt Paneth Cells in a section of small intestine stained with phloxine-tartrazine