Cell Science Reviews

Table of Contents

	Commentaries	Page
	A new light on dopaminergic transmission - Guy S. Bewick	1
	The multifaceted physiology of action potentials in neocortical pyramidal neurons - Jackie Schiller, Alon Korngreen, Alon Polsky & Christiaan P.J. de Kock	6
	An old dog learns a new trick: Synaptotagmin, a Ca2+ sensor for spontaneous release at central synapses - Nikolaos Giagtzoglou, Mingshan Xue & Hugo J. Bellen	19
	Mechanically-ignited calcium flickers: Reemergence of an old role in mechanosensitive regulation of cell migration and the discovery of a new role in chemotaxis - Owen P. Hamill & Rosario Maroto	26
	Spatiotemporal dynamics of Rho GTPase activities during cell protrusion - Joseph G. Duman & Kimberley F. Tolias	32
	Alternative polyadenylation in cancer severs repression by 3’UTR associated factors - Johanna B. Withers & Karen L. Beemon	39
	The road to complete remission: the death of cancer stem cells - Lisa A Kirkwood & Jennifer Southgate	47
	The miR-145 pluripotency loop in human embryonic stem cells - Kitchener D. Wilson & Joseph C. Wu	51
	PACS-2, at the cross roads of ER trafficking and TRAIL-induced apoptosis - Sahru Yüksel & Nesrin Özören	56
	Less TORC is more: Therapeutic extension of mammalian lifespan - ChiKwan Tsang & X.F. Steven Zheng	63
	Like clock work: Pulses of gene regulation by natural glucocorticoid steroid hormones - Iain J. McEwan	73
	Coupling mitochondrial metabolism with insulin secretion: Is matrix alkalinization an activation signal? - Gary W. Cline	82
	One more trick in the regulation of PGC-1α - Zhen Yan	88
	The role of CCK8 in the inhibition of glucose production - Christopher J. Ramnanan, Dale S. Edgerton & Alan D. Cherrington	92
	Featured Reviews
	The emerging role of copy number variation in cancer - Kelsie L. Thu, Wan L. Lam & Bradley P. Coe	98
	Roles of retrotransposons in benign and malignant hematologic disease - Anna M. Schneider, Amy S. Duffield, David E. Symer & Kathleen H. Burns	121
	The emerging role of CCN6 in breast cancer invasion - Guadalupe Lorenzatti, Wei Huang & Celina G. Kleer	146
	Energy balance, obesity and mechanisms for increased cancer risk - Maria Azrad & Tim R. Nagy	158
	Mitochondrial dysfunction & Parkinson's Disease - Anthony K. F. Liou & Jun Chen	179
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