Cell Science Reviews

Table of Contents

	Commentaries	Page
	Phosphoinositide 3-kinase p110α: an Essential Mediator of Ras-driven Tumorigenesis - Christina C. Spevak & David Stokoe	1
	p38α MAP kinase and the proliferation and differentiation of stem cells - David A. Gerber	10
	p38α MAPK as a Negative Regulator of Cell Proliferation - Arianna L. Kim, Joshua Arbesman & David R. Bickers	16
	Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases - David R. Harder, Phillip F. Pratt & Jayashree Narayanan	22
	LTD in cerebellar Purkinje cells: what do spines have to do with it? - Hayley A. Mattison, Michael W. Nestor & Scott M. Thompson	26
	Bringing together the main players on synaptic potentiation - Maria Victoria Tejada-Simon	37
	OutFOXed: Two distinct FOX/Forkhead transcription factors mediate longevity effects of dietary restriction and insulin-like signaling - Robert J. Shmookler Reis	45
	SNPshots of Type 2 Diabetes Genes: From Analog to Digital Genomics - Renee C. LeBoeuf	52
	Featured Reviews
	Synaptic trapping of AMPA receptors - Peter Hastie & Lu Chen	60
	Neuronal forward signalling: novel aspects of molecular signal transduction from dendrites to axons - Margarethe Bittins & Hans-Hermann Gerdes	83
	Astrocytic Exocytosis of Glutamate by a Large Vesicle - Jian Kang	96
	Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration - Alison J.B. Markowitz, Michael G. White, Dennis L. Kolson & Kelly L. Jordan-Sciutto	111
	The determination of multipotent intestinal stem cell fate - Cynthia Kosinski & Xin Chen	147
	RNA interference: Relevance in Targeting Ras and Ras-signaling Pathways in Human Cancer - Shirley K. Samuel & Alex W. Tong	170
	Lifespan Increase by Dietary Restriction and Insulin/IGF-1 Signaling Reduction - Douglas M. Ruden, Parsa Rasouli & Xiangyi Lu	197
	Physiological Functions of Neuropeptide S - Rainer K. Reinscheid	209
	The Role of the Agouti-Related Protein in Human Energy Balance Regulation - Olha Ilnytska & George Argyropoulos	231
	Clinical implications of two-pore potassium channels in brain - Ethan M. Goldberg	250
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